(2Z)-(2-amino-1,3-thiazol-4-yl)[(2-tert-butoxy-2-oxoethoxy)imino]ethanoic acid
( Z )-2-(2-Aminothiazol-4-yl)-2-(t-butoxycarbonylmethoxyimino)acetic acid
CAS: 74440-02-1
Molecular Formula: C11H15N3O5S
(2Z)-(2-amino-1,3-thiazol-4-yl)[(2-tert-butoxy-2-oxoethoxy)imino]ethanoic acid - Names and Identifiers
(2Z)-(2-amino-1,3-thiazol-4-yl)[(2-tert-butoxy-2-oxoethoxy)imino]ethanoic acid - Physico-chemical Properties
| Molecular Formula | C11H15N3O5S |
| Molar Mass | 301.32 |
| Density | 1.43±0.1 g/cm3(Predicted) |
| Melting Point | 175-176 °C (decomp) |
| Boling Point | 482.8±51.0 °C(Predicted) |
| Flash Point | 245.8°C |
| Solubility | DMSO, Methanol (Sparingly) |
| Vapor Presure | 3.93E-10mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 2?+-.0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.601 |
(2Z)-(2-amino-1,3-thiazol-4-yl)[(2-tert-butoxy-2-oxoethoxy)imino]ethanoic acid - Introduction
(Z )-2-(2-Aminothiazol-4-yl)-2-(t-butoxycarbonylmethoxyimino)acetic acid is a compound with the formula C11H15N3O4S. Here are some properties and information about the compound:
Nature:
-Appearance: Colorless or light yellow crystalline powder
-Solubility: Slightly soluble in water
-melting point: about 135-140 ℃
-Molecular weight: 285.32g/mol
-Possible stereoisomers, of which (Z)-form is the dominant isomer
Use:
- ( Z )-2-(2-Aminothiazol-4-yl)-2-(t-butoxycarbonylmethoxyimino)acetic acid is a commonly used intermediate compound, often used in organic synthesis reactions.
-It can be used to synthesize other aminothiazole derivatives.
Preparation Method:
the synthesis method of (Z )-2-(2-Aminothiazol-4-yl)-2-(t-butoxycarbonylmethoxyimino)acetic acid is relatively complicated, and the commonly used methods include the following steps:
1. First, 2-aminothiazol-4-ol and dimethylmethyleneamine undergo an amidation reaction to generate 2-(2-aminothiazol-4-yl) acetamide.
2. Next, 2-(2-aminothiazol-4-yl) acetamide is reacted with tert-butoxycarbonylketone to produce 2-(2-aminothiazol-4-yl)-2-tert-butoxycarbonylacetic acid.
3. finally, the obtained compound is reacted with sodium carbonyldiazenecarboxylate to obtain (Z )-2-(2-Aminothiazol-4-yl)-2-(t-butoxycarbonylmethoxyimino)acetic acid.
Safety Information:
There is limited information regarding the safety of (Z )-2-(2-Aminothiazol-4-yl)-2-(t-butoxycarbonylmethoxyimino)acetic acid. As a chemical substance, attention should be paid to its possible harm to the human body. Maintain proper precautions during handling and storage. Detailed safety information should refer to the safety data sheet (SDS) of the relevant chemical. When using this compound, please observe the correct experimental practice.
Nature:
-Appearance: Colorless or light yellow crystalline powder
-Solubility: Slightly soluble in water
-melting point: about 135-140 ℃
-Molecular weight: 285.32g/mol
-Possible stereoisomers, of which (Z)-form is the dominant isomer
Use:
- ( Z )-2-(2-Aminothiazol-4-yl)-2-(t-butoxycarbonylmethoxyimino)acetic acid is a commonly used intermediate compound, often used in organic synthesis reactions.
-It can be used to synthesize other aminothiazole derivatives.
Preparation Method:
the synthesis method of (Z )-2-(2-Aminothiazol-4-yl)-2-(t-butoxycarbonylmethoxyimino)acetic acid is relatively complicated, and the commonly used methods include the following steps:
1. First, 2-aminothiazol-4-ol and dimethylmethyleneamine undergo an amidation reaction to generate 2-(2-aminothiazol-4-yl) acetamide.
2. Next, 2-(2-aminothiazol-4-yl) acetamide is reacted with tert-butoxycarbonylketone to produce 2-(2-aminothiazol-4-yl)-2-tert-butoxycarbonylacetic acid.
3. finally, the obtained compound is reacted with sodium carbonyldiazenecarboxylate to obtain (Z )-2-(2-Aminothiazol-4-yl)-2-(t-butoxycarbonylmethoxyimino)acetic acid.
Safety Information:
There is limited information regarding the safety of (Z )-2-(2-Aminothiazol-4-yl)-2-(t-butoxycarbonylmethoxyimino)acetic acid. As a chemical substance, attention should be paid to its possible harm to the human body. Maintain proper precautions during handling and storage. Detailed safety information should refer to the safety data sheet (SDS) of the relevant chemical. When using this compound, please observe the correct experimental practice.
Last Update：2024-04-10 22:29:15
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Product Name: (Z)-2-(2-Aminothiazol-4-yl)-2-(tert-butoxycarbonylmethoxyimino)acetic Acid Visit Supplier Webpage Request for quotation
CAS: 74440-02-1
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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CAS: 74440-02-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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